How to Give Probiotics with Antibiotics for Dogs

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We all want the best for our dogs. And you may notice that your dog is suffering from diarrhea and other symptoms after being put on antibiotics.

Antibiotics are vitally important if your dog gets a bacterial infection and can even save your dog’s life, just like they have saved countless human lives. However, they can also cause side effects that can result in your dog experiencing discomfort such as diarrhea, nausea, indigestion, stomach pain, and more.

You can’t totally eliminate all of the potential side effects that may come from your dog being on antibiotics but the good news is that you can help alleviate a lot of it and get your dog’s gut health back to normal by giving your dog a high-quality probiotic. There’s just one simple thing you need to know in order to make probiotics effective while your dog is on antibiotics.

Here’s How to Give Probiotics with Antibiotics for Your Dog

Here’s the one thing you need to know: when giving your dog probiotics while they’re on antibiotics, make sure to give your dog the probiotics at least two hours before or after giving them antibiotics.

That’s really the only thing you need to keep in mind when giving your dog probiotics while he or she is on antibiotics but it’s really important that you do so. The reason being is that antibiotics kill virtually any bacteria they come in contact with and the majority of probiotics are bacteria.

If you give your dog probiotics and antibiotics at the same time, the probiotics will likely be wiped out immediately and won’t be able to give your dog their intended health benefits. Probiotics need to get past the stomach and to the gut in order to pass on their health benefits and they need to get there unharmed by things like stomach acid and antibiotics.

By having your dog take antibiotics and probiotics at least two hours apart, the two won’t interact with each other. The antibiotics can do their job of eliminating whatever is infecting your dog and the probiotics will be able to reach the gut and do their job of improving gut health, digestion, and general health.

What Type of Probiotic Product Should You Give Your Dog?

Not all dog probiotic products are made equally so it’s important that you take a few things into consideration when shopping for one.

The first thing you want to keep in mind when shopping for a dog probiotic is the probiotic strains that the product contains. Ideally, you want a probiotic product that contains a wide range of probiotic strains (for a wide range of health benefits) that have all been scientifically tested and proven safe and effective in dogs.

Some of the probiotic strains to look for include:

  • Bacillus coagulans
  • Bacillus subtilis
  • Bifidobacterium animalis
  • Bifidobacterium bifidum
  • Bifidobacterium breve
  • Bifidobacterium lactis
  • Enterococcus faecium
  • Lactobacillus acidophilus
  • Lactobacillus casei
  • Lactobacillus fermentum
  • Lactobacillus plantarum
  • Lactobacillus rhamnosus
  • Lactobacillus reuteri

You should also look for a product that transparently lists all ingredients on the label, including the ingredients that aren’t probiotic strains.

A high-quality probiotic dog product will have a label that tells you how many probiotic microorganisms will be in a serving of the product at the end of its shelf life. This is measured in CFU, or colony-forming units. A high-quality probiotic product for dogs will also have a use-before date.

Another important thing to keep in mind when shopping for a probiotic supplement is the form that it comes in. Probiotics for dogs come in soft/hard treats, powders, tablets, capsules and more.

Soft chew treats are the superior option. Getting your dog to eat a treat is much easier than getting them to eat something like a powder or tablet.

Hard treats can work too but hard treats can actually damage your dog’s teeth, so soft chews are what you should be giving your dogs for any kind of treats that you give them.


Antibiotics are necessary for fighting off infections but they have side effects that can cause your dog discomfort. Antibiotics wipe out the microbiome, which can make gut health suffer and they can cause side effects like diarrhea and indigestion. You can help restore your dog’s microbiome and relieve the side effects of antibiotics by giving them probiotics.

In terms of how to give probiotics with antibiotics for dogs, the important thing to do is to give your dog probiotics either two hours before or after you give them their dose of antibiotics so that the two don’t interact with each other. Otherwise, the antibiotics will kill the probiotics.